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HIV-1 Subtype C Vpr Amino Acid Residue 45Y and Specific Conserved Fragments Are Associated with Neurocognitive Impairment and Markers of Viral Load

期刊: AIDS RESEARCH AND HUMAN RETROVIRUSES, 2023; 39 (4)

There is increasing evidence that HIV-1 viral protein R (Vpr) plays an important role in the pathogenesis of cognitive impairment. We investigated the......

Demographic and Clinical Characteristics of Persons with HIV with Viral Load:Adherence Mismatch Who Are at Risk of Future Viremia

期刊: AIDS RESEARCH AND HUMAN RETROVIRUSES, 2023; 39 (1)

The potency of modern antiretroviral therapy (ART) allows for greater forgiveness to missed doses while still achieving, and maintaining, viral suppre......

Immune Cell Cross Talk in the Establishment of Human Immunodeficiency Virus-1 Latency

期刊: AIDS RESEARCH AND HUMAN RETROVIRUSES, 2023; 39 (7)

Revolutionary progress in combinational antiretroviral therapy has transformed human immunodeficiency virus (HIV) infection into a chronic manageable ......

The Burden of Pretreatment HIV Drug Resistance in Trinidad and Tobago

期刊: AIDS RESEARCH AND HUMAN RETROVIRUSES, 2023; ()

Strategies to improve the scale-up of antiretroviral therapy (ART) for patients with HIV in Trinidad and Tobago, including the adoption of the Test an......

Mixed Origins: HIV gp120-Specific Memory Develops from Pre-Existing Memory and Naive B Cells Following Vaccination in Humans

期刊: AIDS RESEARCH AND HUMAN RETROVIRUSES, 2023; 39 (7)

The most potent and broad HIV envelope (Env)-specific antibodies often when reverted to their inferred germline versions representing the naive B cell......

Effects of Gender and Baseline CD4 Count on Post-Treatment CD4 Count Recovery and Outcomes in Patients with Advanced HIV Disease: A Retrospective Cohort Study

期刊: AIDS RESEARCH AND HUMAN RETROVIRUSES, 2023; 39 (7)

Presentation to care with advanced HIV disease (AHD) is a significant problem in sub-Saharan Africa. We evaluated factors associated with immune recov......

Examining the Association Between a Modified Quan-Charlson Comorbidity Index and HIV Viral Suppression: A Cross-Sectional Analysis of DC Cohort Participants

期刊: AIDS RESEARCH AND HUMAN RETROVIRUSES, 2023; 39 (12)

With the advancement of effective antiretroviral therapy, people with HIV live longer, and many are developing non-AIDS comorbidities. It is important......

Integrase Strand Transfer Inhibitor Use in Children with Perinatal HIV-1 Infection: A Narrative Review

期刊: AIDS RESEARCH AND HUMAN RETROVIRUSES, 2023; 39 (6)

Integrase strand transfer inhibitors (INSTIs), including raltegravir (RAL), dolutegravir (DTG), elvitegravir (EVG), bictegravir (BIC), and cabotegravi......

Highly Ambiguous HIV-1 Pol Positions Encoding Multiple Amino Acids Usually Result from Antiviral or Immune Selection Pressure

期刊: AIDS RESEARCH AND HUMAN RETROVIRUSES, 2023; 39 (3)

HIV-1 pol nucleotide ambiguities encoding amino acid mixtures occur commonly during population-based genotypic drug resistance testing. However, few s......

Replacement of Antiretroviral Therapy with HIV Broadly Neutralizing Antibodies to Maximize the Effectiveness of Chemotherapy in HIV Patients with Lung Cancer

期刊: AIDS RESEARCH AND HUMAN RETROVIRUSES, 2023; 39 (9)

Non-small cell lung cancer (NSCLC) is the most fatal non-AIDS defining cancer in people living with HIV (PWH) on antiretroviral therapy (ART). Treatme......

Chronic Kidney Disease and Accelerated Decline of Renal Function in Older Adults with HIV in Northern Thailand

期刊: AIDS RESEARCH AND HUMAN RETROVIRUSES, 2023; 39 (12)

Kidney disease remains prevalent in people living with HIV even in the antiretroviral treatment era. We determine the frequency of chronic kidney dise......

Switching from Tenofovir Disoproxil to Tenofovir Alafenamide Fumarate: Impact on Cardiovascular Risk and Lipid Profile in People Living with HIV, an Observational Study

期刊: AIDS RESEARCH AND HUMAN RETROVIRUSES, 2023; 39 (2)

In the era of combination antiretroviral therapy (ART), people living with HIV (PLHIV) still face an increased risk of cardiovascular disease (CVD). T......

Ex Vivo Colonic Tissue Susceptibility to HIV-1 in Cisgender Men and Women

期刊: AIDS RESEARCH AND HUMAN RETROVIRUSES, 2023; ()

The biology of HIV-1 acquisition through unprotected receptive anal intercourse is understudied. Considering that sex hormones are implicated in intes......

Association of Viral and Host Genetic Architecture with the Status of Neurocognitive Disorder in HIV-Infected Individuals

期刊: AIDS RESEARCH AND HUMAN RETROVIRUSES, 2023; 39 (12)

The polymorphisms in host genes such as CCR5, CCR2, stromal derived factor (SDF), and MBL (mannose-binding lectin) as well as the viral nef gene have ......

HIV Incidence, Recent HIV Infection, and Associated Factors, Kenya, 2007-2018

期刊: AIDS RESEARCH AND HUMAN RETROVIRUSES, 2023; 39 (2)

Nationally representative surveys provide an opportunity to assess trends in recent human immunodeficiency virus (HIV) infection based on assays for r......

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